Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia

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Recurrent Bacterial Meningitis in a Child with Mondini Dysplasia

Mondini dysplasia, also known as Mondini malformation, is a developmental abnormality of the inner and middle ears that can cause hearing loss, cerebrospinal fluid (CSF) leakage, and recurrent bacterial meningitis (RBM), which is defined as two or more episodes of meningitis separated by a period of convalescence and the complete resolution of all signs and symptoms. An accurate diagnosis of th...

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Multicystic Renal Dysplasia in a Child with Split Hand/Split Foot Malformation

Split hand/split foot malformation is a human developmental disorder characterized by missing central digits and other distal limb malformations. Multicystic renal dysplasia is the most common cause of an abdominal mass in the new born period and is the most common cystic malformation of the kidney in infancy. Here, we report a case of split hand/split foot malformation with a submucosed cleft ...

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Refinement of the deletion in 7q21.3 associated with split hand/foot malformation type 1 and Mondini dysplasia.

S plit hand/foot malformation type I (SHFM1, OMIM *183600) is an autosomal dominant developmental disorder of limb formation that results in the absence of the central digital rays, deep median clefts, and syndactyly of the remaining digits. Patients with SHFM1 harbour deletions, translocations, and inversions in chromosomal region 7q21–q22. The deletions at 7q21–q22 encompass different genomic...

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ELECTRONIC LETTER Refinement of the deletion in 7q21.3 associated with split hand/foot malformation type 1 and Mondini dysplasia

S plit hand/foot malformation type I (SHFM1, OMIM *183600) is an autosomal dominant developmental disorder of limb formation that results in the absence of the central digital rays, deep median clefts, and syndactyly of the remaining digits. Patients with SHFM1 harbour deletions, translocations, and inversions in chromosomal region 7q21–q22. The deletions at 7q21–q22 encompass different genomic...

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recurrent bacterial meningitis in a child with hearing impairment, mondini dysplasia: a case report

recurrent bacterial meningitis is not a common disease and makes physicians seek underlying predisposing factors which can result from anatomic anomalies or immunodeficiency. in this paper we present a boy with recurrent bacterial meningitis with the history of trauma and sensorineural hearing loss. mondini dysplasia was demonstrated with computed homographic scans (ct-scan) of temporal bones.

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ژورنال

عنوان ژورنال: Journal of Developmental and Physical Disabilities

سال: 2015

ISSN: 1056-263X,1573-3580

DOI: 10.1007/s10882-015-9460-2